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Molecules ; 27(15)2022 Jul 25.
Article in English | MEDLINE | ID: covidwho-1994112

ABSTRACT

A set of heterocyclic products was synthesized from natural (+)-camphor and semi-synthetic (-)-camphor. Then, 2-Imino-4-thiazolidinones and 2,3-dihydrothiazoles were obtained using a three-step procedure. For the synthesized compounds, their antiviral activity against the vaccinia virus and Marburg virus was studied. New promising agents active against both viruses were found among the tested compounds.


Subject(s)
Antiviral Agents , Camphor , Antiviral Agents/pharmacology , Camphor/pharmacology , Structure-Activity Relationship , Thiazoles/pharmacology
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